Not known Details About https://www.ceesdekker.net
Not known Details About https://www.ceesdekker.net
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‘Of course, that's about ideal. I look for a Actual physical understanding of biological devices in a bottom-up way. I feel you could distinguish 3 traces of investigate in my group in the intervening time. The very first considerations chromosome framework: how do you get yourself a metre-very long DNA polymer folded and organised in this kind of microscopic cell? We've got formulated visualisation procedures that permit us to review how, for example, SMC proteins loop DNA (video on Youtube) as a way to Make up chromosomes.
Our group scientific studies bacterial cell division and is particularly aiming to represent a ‘bottom up biology’ in artificial cells which can autonomously divide. Our key fascination lies in mobile division, chromatin composition, and spatial Management.
, Groningen scientists present the results in their attempts to make labs more sustainable and supply techniques for other labs.
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
We develop issue-of-treatment diagnostics check of neglected tropical illnesses in just useful resource-constrained settings, dependant on Crspr/Cas9 detecting of pathogen’s DNA in system fluids.
During the decades pursuing these discoveries, my investigation passions shifted to biophysics and nanobiology, and I turned fewer involved with the development of nanotube electronics. The focus of numerous researchers in the field also shifted to graphene (where, funnily more than enough, the main graphene ribbons ended up referred to as ‘nanotubes which are cut open up alongside their length’) just after the discovery of the two-dimensional substance in 2004.
‘At the beginning we looked at biological programs which has a Bodily watch and acted on The premise from the equipment we realized. It took a few years just before we started off Doing the job much more on the large Organic difficulties. I then began to contact it nanobiology, a phrase that did not exist at enough time.
Learning DNA loop extrusion by cees dekker SMC proteins for chromosome architecture with one-molecule assays.
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It had been through this era that Dekker performed research on magnetic spin methods and on noise in superconductors and semiconductors.
FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial mobile division
Afterwards we spoke once again briefly mainly because Dekker felt that our dialogue of his faith swiftly grew to become purely philosophical, While In addition it concretely assists him in his perform.
Allow’s 1st appear again at the moment whenever you decided to shift your target from superconductivity and nanotubes to biology at the end of the nineties.
2013, managed shaping of Reside bacterial cells into arbitrary styles; and discovery of spontaneous fluctuations inside the handedness of histone tetrasomes